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Tid-Bits: Oral Potentially Malignant Disorders and Epithelial Dysplasia

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Tid-Bits: Oral Potentially Malignant Disorders and Epithelial Dysplasia

HackDentistry
May 10, 2023
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Tid-Bits: Oral Potentially Malignant Disorders and Epithelial Dysplasia

hackdentistry.substack.com

On the website this lesson in the Chapter - “Oral Pathology Tid-Bits” in the Revision Ninja - Oral Pathology course bundle addresses 4 key questions in relation to Oral Potentially Malignant Disorders (OPMDs) and Epithelial Dysplasia (psst…this is also a free lesson on our website by the way).

Key Questions

  1. What’s the deal with precancerous lesions, precancerous conditions and oral potentially malignant disorders? I am confused with these terms.

  2. Is epithelial dysplasia a significant predictor of malignant transformation of OPMDs?

  3. Is Proliferative Verrucous Leukoplakia a distinct entity?

  4. Besides epithelial dysplasia, can the site and clinical appearance of an OPMD like leukoplakia be a predictor of malignant transformation? 


Q: Is epithelial dysplasia a significant predictor of malignant transformation of Oral Potentially Malignant Disorders (OPMDs)?

A: It sort of "is" and "is not". Before you get confused let me explain.

The microscopic evaluation for the presence of epithelial dysplasia in OPMDs remains the gold standard for the assessment of these lesions. It is believed that OPMDs with epithelial dysplasia have more chances of malignant transformation. Currently available molecular markers have not been proved to be of able predictors of malignant transformation.

However, it has to be remembered that it is not inevitable that a dysplastic lesion will transform into cancer. There is evidence of dysplastic lesions not progressing to carcinoma and also OPMDs without evidence of dysplasia progressing to cancer.


🔎You could delve into the other questions too

This is a free lesson available to read in the free sample course 👉 The Free Stuff on our website - www.hackdentistry.com!

Read the rest of the article (Free)


🎥 Video!

Psst! A video for this is on the works too! It’ll be posted on YouTube and I shall notify you of the same, hopefully soon :)


📚Study resources on HackDentistry!

  • Revision Ninja - Oral Pathology (Notes, Videos & MCQs)

  • Revision Ninja - Oral Histology (Notes, Videos & MCQs)

  • Revision Ninja - Periodontics (Notes & MCQs)

  • Question Bank (5000+ Questions)

View all Syllabus/Topics covered

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Tid-Bits: Oral Potentially Malignant Disorders and Epithelial Dysplasia

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