Are you up for a Q and A challenge?
👋Hey peeps!
Hopefully you guys are up for a Q and A challenge today. Here's the deal. 👨🏫I'll ask you a bunch of questions and hopefully you would do some homework and answer them.
Mind you the questions, though not difficult, may require some reading. So feel free to browse our website or go through your textbooks for an answer. So, moving on to the questions!
📝Questions
Would dentigerous cyst show its characteristic histopathology picture if it was infected/inflamed?
The different histology patterns of ameloblastoma correlate with the prognosis of the tumor. Follicular pattern has best prognosis and the granular pattern has the worst prognosis. Is this true?
Is periapical granuloma a granulomatous infection?
Are Grinspan syndrome and Greenspan lesion the same?
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💡Scroll down👇 for the answers if you get stuck!
📚Here are some resources you could read from
Revision Ninja - Oral Pathology and Medicine(Notes, Videos & MCQs)
Neville BW, Damm DD, Allen CM, Chi A. Oral and Maxillofacial Pathology. South Asian ed. Elsevier; 2016.
Rajendran R, Sivapathasundaram B. Shafer’s Textbook of Oral Pathology. 7th ed. Elsevier; 2012.
Regezzi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 5 th ed. Elsevier; 2007.
📚Study resources on HackDentistry!
Answers👇
Would dentigerous cyst show its characteristic histopathology picture if it was infected/inflamed?
Ans 👉 It wouldn’t! An inflamed dentigerous cyst would show moderate to dense inflammation of the connective tissue. The connective tissue would also become more collagenous/fibrous. Also the epithelium may become hyperplastic, and develop rete ridges.
The different histology patterns of ameloblastoma correlate with the prognosis of the tumor. Follicular pattern has best prognosis and the granular pattern has the worst prognosis. Is this true?
Ans👉 Nope! The histology patterns of ameloblastoma have no association or correlation with its clinical behaviour. Conventional ameloblastomas, irrespective of their histological appearance are aggressive and have to be treated accordingly. Separation of ameloblastoma into various histologic subtypes is only academic and has no bearing on treatment.
Is periapical granuloma a granulomatous infection?
Ans👉 Nope! Peri-apical granuloma is wrongly termed “granuloma” and is actually a localized mass of chronically inflamed granulation tissue! While granulation tissue and granuloma, are both a product of chronic inflammation, they are entirely different types of inflammatory tissue reactions.
Granuloma is a product of cell-mediated immune response, a type-IV hypersensitivity reaction caused by agents like bacteria or fungi. Eg – Tuberculosis, Blastomycosis.
Peri-apical granuloma is a mass of reparative granulation tissue which forms as a defensive reaction to microbial infection seeping into the peri-apex from the overlying tooth.
Are Grinspan syndrome and Greenspan lesion the same?
Ans 👉Nope, they are not! Oral lichen planus (OLP) was previously thought to be associated with diabetes mellitus and hypertension and this triad of conditions was called Grinspan’s syndrome. However, there is no evidence for OLP’s association with the other two conditions. OLP in patients with diabetes and hypertension most likely represents oral lichenoid lesion (OLL), in response to the medications used.
Greenspan lesion is an alternative term for “hairy leukoplakia”. Hairy leukoplakia is a white corrugated lesion primarily affecting the lateral borders of the tongue. It is seen in patients with severe immunosuppression especially those infected with AIDS.