Are you up for a Q and A challenge? Issue 4
👋Hey peeps!
Hopefully you guys are up for a Q and A challenge today. Here's the deal. 👨🏫I'll ask you a bunch of questions and hopefully you would do some homework and answer them.
Mind you the questions, though not difficult, may require some reading. So feel free to browse our website or go through your textbooks for an answer. So, moving on to the questions!
📝Questions
How is dysplastic dentin or dentinoid formed?
Orthokeratinized odontogenic cyst (OOC) is a variant of OKC. Is this true?
Can OKC undergo a malignant transformation to squamous cell carcinoma?
Why do you think there may be cholesterol clefts formed in the connective tissue in radicular cyst?
💡Scroll down👇 for the answers if you get stuck!
📚Here are some resources you could read from
Revision Ninja - Oral Pathology and Medicine(Notes, Videos & MCQs)
Neville BW, Damm DD, Allen CM, Chi A. Oral and Maxillofacial Pathology. South Asian ed. Elsevier; 2016.
Rajendran R, Sivapathasundaram B. Shafer’s Textbook of Oral Pathology. 7th ed. Elsevier; 2012.
Regezzi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 5 th ed. Elsevier; 2007.
🔎You could dig deeper!
Apart from Revision Ninja, you could also get access to 5000+ quiz questions across 21 subjects in dentistry with the Question Bank bundle!
📚Other study resources on HackDentistry!
Answers👇
How is dysplastic dentin or dentinoid formed?
Ans 👉 Dysplastic dentin or dentinoid is thought to be dentin like material that arises as a result of an inductive effect of the odontogenic epithelium on the connective tissue cells. This is pretty much like inner enamel epithelium/ameloblasts inducing the dental papilla cells to become odontoblasts, which then secrete dentin.
Orthokeratinized odontogenic cyst (OOC) is a variant of OKC. Is this true?
Ans 👉 Nope, OOC is not a variant of OKC!
Orthokeratinized odontogenic cyst (OOC) was first described as an orthokeratinizing variant of odontogenic keratocyst (OKC) in 1981. The basis of this distinction was the difference in its histopathology and its reduced chances of recurrence as compared to OKC.
It is now known and accepted that OOC is a distinct clinic-pathologic entity on its own. In fact it has been listed as a developmental odontogenic cyst in the recent (2017) WHO classification of odontogenic cysts.
Can OKC undergo a malignant transformation to squamous cell carcinoma?
Ans 👉 Yes, OKC has been reported to undergo malignant transformation to oral squamous cell carcinoma although very rarely.
Why do you think there may be cholesterol clefts formed in the connective tissue in radicular cyst?
Ans 👉 Cholesterol clefts are formed due to accumulation of cholesterol in the connective tissue, which then gets dissolved out during histologic preparations forming clefts. These cholesterol accumulations are hypothesized to be derived from the cell walls of disintegrating red blood cells, lymphocytes, plasma cells and macrophages.