Video - Sjogren's Syndrome

Sjogren's syndrome (SS) is an autoimmune, chronic inflammatory disease affecting exocrine glands, primarily the salivary and lacrimal glands. It is characterized by infiltration of T-cells in these glands, causing destruction and functional impairment. Other exocrine glands affected may include those in the gastrointestinal tract, skin and vagina.

💡Sjogren’s syndrome may manifest as

1. Primary Sjogren's syndrome -> Only the salivary and lacrimal glands are affected, causing xerostomia (dry mouth) and xerophthalmia (dry eyes). This is also called "Sicca syndrome" 

2. Secondary Sjogren's syndrome -> Apart from Sicca syndrome, the patient may also have other associated auto-immune diseases like rheumatoid arthritis, scleroderma, systemic lupus erythematosus (SLE) and polymyositis.

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🎥 Video

Sjogren's syndrome (Part 1) - Etiology and Pathogenesis

Sjogren's syndrome (Part 2) - Clinical features and Histopathology

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