Verrucous carcinoma's deceptive cousin!
Shear and Pindborb in 1980 reported lesions of the oral cavity that were clinically indistinguishable from verrucous carcinoma (VC) but showed slight differences under the microscope. They called them “Verrucous Hyperplasia” (VH).
In order to bring some uniformity in reporting this lesion, an expert group of Oral Pathologists held a consensus meeting in Malaysia in 2013. They formulated a set of clinico-pathologic features and proposed the term “Exophytic Verrucous Hyperplasia”.
VH mainly differentiates itself from VC in the absence of an endophytic growth of the epithelium. The broad rete ridges are rather in the same level as the adjacent normal epithelium and do not extend deep into the connective tissue unlike VC.
It has in fact been reported to be a distinct entity in the Indian population and pathologists consider it to be a potentially malignant disorder, though it has not been classified as one by the World Health Organization.
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